منابع مشابه
CPT: Pharmacometrics & Systems Pharmacology
QSP-10 APPLICATION OF AN IN SILICO PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL TO SIMULATE ORAL DRUG BIOAVAILABILITY OF ATORVASTATIN ACID AND CYCLOSPORINE POST BARIATRIC SURGERY. A. S. Darwich,1 D. Pade,2 K. Rowland-Yeo,2 M. Jamei,2 A. Åsberg,3 H. Christensen,3 D. M. Ashcroft,1 A. Rostami-Hodjegan1; 1Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, United Kingd...
متن کاملSystems biology and pharmacology.
Drug action depends not only on the direct consequences of the interaction between the drug and its target but also on other consequences within the complex physiological system that is the human body. The National Institute of General Medical Sciences (NIGMS) has brought together investigators from the emerging field of systems biology with pharmacologists to explore possible avenues for utili...
متن کاملEyes on systems pharmacology.
As an emerging subdiscipline of pharmacology, one of the priary goals of systems pharmacology is to elucidate therapeutic echanisms of combined pharmacological strategies used to treat iverse complex diseases in which multiple integrated cellular athways are perturbed. Mechanistic insights into disease pathogenesis are critical for ptimal therapeutic development. With the exception of rare onoo...
متن کاملSystems Pharmacology and Pharmacodynamics
Reviewed by Piet H. van der Graaf In 2008 and 2010, the National Institute of General Medical Sciences of the National Institutes of Health sponsored two workshops that resulted in the 2011 white paper “Quantitative and Systems Pharmacology in the Post-genomic Era: New Approaches to Discovering Drugs and Understanding Therapeutic Mechanisms,” which is widely accepted to be a milestone marking t...
متن کاملCPT: Pharmacometrics and Systems Pharmacology
Welcome to the first issue of CPT: Pharmacometrics and Systems Pharmacology (CPT:PSP), a new journal from the American Society for Clinical Pharmacology and Therapeutics. CPT:PSP is a cross-disciplinary journal devoted to publishing advances in quantitative, model-based approaches as applied in pharmacology, (patho)physiology, and disease to aid the discovery, development, and utilization of hu...
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ژورنال
عنوان ژورنال: Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine
سال: 2010
ISSN: 0027-2507
DOI: 10.1002/msj.20191